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Liposuction Subcutaneous Fat Removal Ineffective for Diabetes Prevention
Lipoplasty Doesn't Offer Metabolic Benefits for Diabetics
Liposuction Ineffective for Diabetes Prevention
Liposuction is no substitute for dieting when it comes to preventing diabetes, hypertension and heart disease.
Subcutaneous Fat Reduction
"Despite removing large amounts of subcutaneous fat about 20 percent of our subject's total body fat mass there were no beneficial medical effects," says Samuel Klein, M.D., the Danforth Professor of Medicine and Nutritional Science, and the study's principal investigator. "Had these subjects lost this much fat by dieting, we would have expected to see marked improvements in insulin sensitivity and other risk factors for heart disease."
Klein and his colleagues studied 15 obese women with excessive abdominal fat eight with normal glucose tolerance and seven with type 2 diabetes before abdominal liposuction and again 10-12 weeks after surgery. The sensitivity of the liver, muscle and fat tissue to insulin was measured by performing an insulin clamp procedure. The clamp technique allows scientists to measure insulin's major metabolic effects, such as how well insulin suppresses liver glucose production and fat breakdown and how well insulin stimulates glucose uptake by muscle tissue. The researchers also measured triglyceride and cholesterol levels, blood pressure and other risk factors for heart disease.
"It was remarkable how similar the results were before and after the procedure," Klein said. "There were no changes in insulin sensitivity, blood lipids, blood pressure or inflammatory markers associated with coronary heart disease in any of our study subjects."
Safety of Large Volume Liposuction
On the plus side, the study did demonstrate it was possible to safely remove large amounts of fat. "We confirmed that it is possible to do large-volume liposuction safely," said co-investigator V. Leroy Young, M.D., a private- practice physician and former professor of plastic and reconstructive surgery at the University. "In the past, we usually removed no more than about five liters of fat, but in this study we showed you can safely remove four times that amount."
"This study underscores the need for the 'old-fashioned' method of eating less and exercising more to treat obesity. The metabolic benefits of weight loss seem to be related to achieving a negative energy balance consuming fewer calories than you burn rather than simply eliminating fat cells by liposuction."
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Laparoscopic or open bariatric surgery, such as gastric banding or bypass is not an easy solution to morbid obesity and weight loss. It is a serious surgical procedure, involving health risks. To produce lasting weight loss it requires a long-term patient commitment to eating a healthy diet and following a regular program of physical exercise. Life-long use of nutritional supplements may also be necessary. So, before deciding, discuss your options fully with your doctor. © 2003-2017 Bariatric-Surgery.Info - Terms - Contact - Information - Resources